{"id":1183,"date":"2018-03-28T15:35:11","date_gmt":"2018-03-28T19:35:11","guid":{"rendered":"https:\/\/woundmd.local\/?p=1183"},"modified":"2021-11-22T15:46:19","modified_gmt":"2021-11-22T20:46:19","slug":"mechanism-of-action-of-amniotic-ecm-treatment","status":"publish","type":"post","link":"https:\/\/woundmdhealth.com\/blog\/mechanism-of-action-of-amniotic-ecm-treatment\/","title":{"rendered":"Mechanism of Action of Amniotic ECM Treatment"},"content":{"rendered":"<div class=\"entry-content\">\n<p><strong>Dr. Jose A. Rivera, DPM, FABFAS<\/strong><\/p>\n<p><strong>Director, Foot &amp; Ankle Services at OrthoRegenX<\/strong><\/p>\n<p>While traditional amniotic products don\u2019t have live stem cells, they do have two interesting things going for them. First, they may have unique cytokines and growth factors that may help tissue healing.\u00a0 Second, and likely more important, is that they are likely an all-purpose ECM.<\/p>\n<p>It has been demonstrated that various ECM products help change the environment for healing. Basically, they are able to take local macrophages (the cells that help repair by taking out the garbage) to go from an M1 state (pro-inflammation and breakdown) to an M2 state (pro-growth and repair). So the efficacy of amnion may be more about its ability to shift a chronic injury site from scarring, swelling, and poor repair to lower inflammation and repair.<\/p>\n<p>Our OrthoRegenX providers have the ability to offer patients a variety of Regenerative treatment options. For more information, you may visit us at www.orthoregenx.com or contact us at 407-720-4253 or hello@orthoregenx.com.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Jose A. Rivera, DPM, FABFAS Director, Foot &amp; Ankle Services at OrthoRegenX While traditional amniotic products don\u2019t have live stem cells, they do have two interesting things going for them. First, they may have unique cytokines and growth factors that may help tissue healing.\u00a0 Second, and likely more important, is that they are likely <\/p>\n","protected":false},"author":1,"featured_media":1184,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[10],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Mechanism of Action of Amniotic ECM Treatment | Wound MD<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/woundmdhealth.com\/blog\/mechanism-of-action-of-amniotic-ecm-treatment\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mechanism of Action of Amniotic ECM Treatment | Wound MD\" \/>\n<meta property=\"og:description\" content=\"Dr. Jose A. Rivera, DPM, FABFAS Director, Foot &amp; Ankle Services at OrthoRegenX While traditional amniotic products don\u2019t have live stem cells, they do have two interesting things going for them. First, they may have unique cytokines and growth factors that may help tissue healing.\u00a0 Second, and likely more important, is that they are likely\" \/>\n<meta property=\"og:url\" content=\"https:\/\/woundmdhealth.com\/blog\/mechanism-of-action-of-amniotic-ecm-treatment\/\" \/>\n<meta property=\"og:site_name\" content=\"Wound MD\" \/>\n<meta property=\"article:published_time\" content=\"2018-03-28T19:35:11+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-11-22T20:46:19+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/woundmdhealth.com\/wp-content\/uploads\/2021\/11\/amniotic-injection.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"467\" \/>\n\t<meta property=\"og:image:height\" content=\"700\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"chatterbuzz\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"chatterbuzz\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/woundmdhealth.com\/blog\/mechanism-of-action-of-amniotic-ecm-treatment\/\",\"url\":\"https:\/\/woundmdhealth.com\/blog\/mechanism-of-action-of-amniotic-ecm-treatment\/\",\"name\":\"Mechanism of Action of Amniotic ECM Treatment | Wound MD\",\"isPartOf\":{\"@id\":\"https:\/\/woundmdhealth.com\/#website\"},\"datePublished\":\"2018-03-28T19:35:11+00:00\",\"dateModified\":\"2021-11-22T20:46:19+00:00\",\"author\":{\"@id\":\"https:\/\/woundmdhealth.com\/#\/schema\/person\/89eb580cd22da32b01baeda059b9412c\"},\"breadcrumb\":{\"@id\":\"https:\/\/woundmdhealth.com\/blog\/mechanism-of-action-of-amniotic-ecm-treatment\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/woundmdhealth.com\/blog\/mechanism-of-action-of-amniotic-ecm-treatment\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/woundmdhealth.com\/blog\/mechanism-of-action-of-amniotic-ecm-treatment\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/woundmdhealth.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Mechanism of Action of Amniotic ECM Treatment\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/woundmdhealth.com\/#website\",\"url\":\"https:\/\/woundmdhealth.com\/\",\"name\":\"Wound MD\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/woundmdhealth.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/woundmdhealth.com\/#\/schema\/person\/89eb580cd22da32b01baeda059b9412c\",\"name\":\"chatterbuzz\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/woundmdhealth.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/woundmdhealth.com\/wp-content\/wphb-cache\/gravatar\/5ce\/5cea1e1dd9dc22f04d26433122f13cf3x96.jpg\",\"contentUrl\":\"https:\/\/woundmdhealth.com\/wp-content\/wphb-cache\/gravatar\/5ce\/5cea1e1dd9dc22f04d26433122f13cf3x96.jpg\",\"caption\":\"chatterbuzz\"},\"sameAs\":[\"https:\/\/woundmdhealth.com\"],\"url\":\"https:\/\/woundmdhealth.com\/blog\/author\/chatterbuzz\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Mechanism of Action of Amniotic ECM Treatment | Wound MD","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/woundmdhealth.com\/blog\/mechanism-of-action-of-amniotic-ecm-treatment\/","og_locale":"en_US","og_type":"article","og_title":"Mechanism of Action of Amniotic ECM Treatment | Wound MD","og_description":"Dr. Jose A. 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